Martínez-López Lab
General description
The Martínez-López Lab investigates interactions between the nervous and immune systems, focusing on how antigen-presenting cells—particularly dendritic cells—decode stress-derived signals. The group studies how these neuroimmune crosstalk mechanisms shape host immunity throughout the lifespan and contribute to pathological processes in cancer and autoimmunity. By combining state-of-the-art techniques, including spectral flow cytometry, high-resolution microscopy, in vivo mouse models, optogenetics, chemogenetics, and single-cell transcriptomics, the lab aims to identify novel molecular targets for the treatment of chronic inflammatory conditions.
The Martínez-López Lab investigates interactions between the nervous and immune systems, focusing on how antigen-presenting cells—particularly dendritic cells—decode stress-derived signals. The group studies how these neuroimmune crosstalk mechanisms shape host immunity throughout the lifespan and contribute to pathological processes in cancer and autoimmunity. By combining state-of-the-art techniques, including spectral flow cytometry, high-resolution microscopy, in vivo mouse models, optogenetics, chemogenetics, and single-cell transcriptomics, the lab aims to identify novel molecular targets for the treatment of chronic inflammatory conditions.
Principal investigator
María Martínez López
Junior Group Leader